GROUP NEWS
Our PNAS paper on PCNA ubiquitylation has been selected and evaluated by the post-publication peer review service Faculty of 1000 (F1000). According to the F1000 service this places our work in ".. the top 2% of published articles in biology and medicine".
The Oak Ridge Leadership Computing Facility at Oak Ridge National Laboratory highlights our work on PCNA ubiquitylation and translesion synthesis.
Our proposal for computational time on the special purpose Anton machine at the National Resource for Biomedical Supercomputing (NRBSC) in Pittsburgh is approved.
Our collaborative efforts on PCNA ubiquitination with Berkeley Lab, Univ. of Iowa and Univ. of Delaware led to a combined experimental/computational publication currently in press in Proceedings of the National Academy of Science U.S.A.
Ivaylo Ivanov receives NERSC Initiative for Scientific Exploration (NISE) Award.
Our collaboration with the group of Prof. Zheng on histone acetylation has led to a combined experimental/computational paper available from the Journal of Biological Chemistry. A second manuscript on the topic is being prepared.
Ivaylo Ivanov receives a Teragrid award of computational time at the NICS to futher our research efforts on base excision repair. Our proposal entitled "Exploring the Chemical Landscape for Base Excision DNA Repair" was approved to receive 2,500,000 CPU hours under allocation CHE110042.
Ivaylo Ivanov receives a Cleon C. Arrington Research Initiation Grant, which will help with establishing our new research program on eukaryotic clamp loading.
Ivaylo Ivanov attended the Keystone Symposium on DNA Replication and Recombination and presented our new findings on the flexible association of ubiquitin and PCNA.
Two recent papers on ligand-gated ion channels (LGICs) have been published and available from the Biophysical Journal and Proteins: Structure, Function and Bioinformatics.
Our work on PCNA highlighted by the NCCS at Supercomputing 2010 in New Orleans.
Chunli Yan is joining our group as a new postdoctoral scholar. She comes to us from the University of Texas, Austin. Welcome Chunli!
Carlo Guardiani who was with us for a year as a postdoctoral scholar is moving back to Italy to assume a new position at the University of Florence. We all want to thank him for his hard work and for helping set our group on the right track from the very beginning.
Max Xu has successfully completed all requirements for the Ph.D. other than the dissertation and advances to candidacy. Congratulations!
The National Center for Computational Sciences (NCCS) at Oak Ridge National Laboratory highlights our work on DNA replication and repair.
Our first paper from GSU is published and available from the web site of the Journal of the American Chemical Society.
Our renewal proposal through the DOE INCITE initiative was awarded 4,000,000 CPU hours at the leadership computing facility at ORNL. We are gratified that the award exceeded our original request by 400,000 units
For more details about the award refer to the new DOE Office of Science announcement.
A renewal proposal for computational resources through the DOE INCITE initiative has been submitted (07/01/2009). In 2009 our research project entitled "Interplay of AAA+ molecular machines, DNA repair enzymes and sliding clamps at the replication fork: A multiscale approach to modeling replisome assembly and function" was competitively chosen to receive 2,600,000 CPU hours of supercomputing time on the Jaguar machine at Oak Ridge National Lab. In 2010 we expect to receive an additional 3,600,000 units.
For more details about the award refer to the 2009 DOE Office of Science announcement.
Two new members join our group. Carlo Guardiani is a postdoctoral scholar who comes to us from the University of Florence in Italy. Max Xu joins us as an incoming Ph.D student. Welcome!
Yang Zhen joins our research group as a first year Ph.D. student. Yang comes to GSU from Lanzhou University in China. Welcome!
Available Positions
POSTDOCTORAL POSITIONS
The postdoctoral positions in the group have been filled. New positions may become available and will be promptly advertised on this page. Candidates should have a record of accomplishments in computational chemistry/biophysics, preferably involving the application of statistical mechanics and computer simulation methods to biomolecular systems.
To inquire send email to:
iivanov@mccammon.ucsd.edu
Opportunities for Graduate Students
Prospective graduate students are always welcome. Interested candidates should apply to the graduate program in chemistry at Georgia State University. To ensure careful consideration, applicants with computational biology interests are welcome to contact Prof. Ivanov by email :
iivanov@mccammon.ucsd.edu
Undergraduate Research Opportunities
At the intersection of biochemistry, physics, mathematics, and computing, the field of computational biology uses theoretical and computational models to show how cellular activity emerges from molecular behavior. Research in this field deepens our understanding of biology and is poised to yield dramatic advances in medicine and technology.
Opportunities may become available in the group for bright, dedicated undergraduates interested in this new field. A background that includes multivariate calculus, physical chemistry, and some familiarity with computing is ideal.