Curriculum Vitae

Education

Postdoctoral Training at the University of California, San Diego, (USA), under the supervision of Prof. J. Andrew McCammon (since 2005).

PhD. Doctorate Degree in Chemistry from the University of York and the Marie Curie Research Institute, England (2000-2004).

MRes. Masters Degree in Bioinformatics from the University of York, England (1999-2000).

BSc(Hons). Bachelors Degree in Biochemistry from Queen's University, Belfast, N.Ireland (1996-1999).

Recent Publications

Simulating Ras conformational switching: probing nucleotide dependent conformational transitions with accelerated molecular dynamics.
Grant*, Gorfe*, Mccammon (2009) PLoS Comput Biol in press,
( Abstract | PubMed | PDF )

Novel procedure for thermal equilibration in molcecular dynamics simulations.
Gallo, Grant, Teodoro, Melton, Cieplak, Phillips, Stec (2009) Molecular Simulation in press,
( Abstract | PubMed | PDF )

Mapping the nucleotide and isoform-dependent structural and dynamical features of Ras proteins.
Gorfe*, Grant*, Mccammon (2008) Structure 16, 885-896
( Abstract | PubMed | PDF )

Automated function prediction.
Friedberg, Rodrigues, Grant, Godzik (2007) BMC Bioinformatics 8, Suppl 4
( Abstract | PubMed | PDF )

Multivariate analysis of conserved sequence-structure relationships in kinesins: coupling of the active site and a tubulin-binding sub-domain.
Grant, McCammon, Caves, Cross (2007) Journal of Molecular Biology 368, 1231-1248
( Abstract | PubMed | PDF )

Bio3D: An R package for the comparative analysis of protein structures.
Grant, Rodrigues, ElSawy, McCammon, Caves, (2006) Bioinformatics 22, 2695-2696
( Abstract | PubMed | PDF )

Targeted molecular dynamics study of C-loop closure and channel gating in nicotinic receptors.
Cheng X, Wang H, Grant B, Sine SM, McCammon JA (2006) PLoS Comput Biol 2, No. 9.
( Abstract | PubMed | PDF )

sgTarget: a target selection resource for structural genomics.
Rodrigues AP, Grant BJ, Hubbard RE (2006) Nucleic Acids Res 34, No. Web Server issue.
( Abstract | PubMed | PDF )

Channel Opening Motion of [alpha]7 Nicotinic Acetylcholine Receptor as Suggested by Normal Mode Analysis
Cheng X, Lu B, Grant B, Law RJ, Mccammon AJ (2006) Journal of Molecular Biology 355, No. 2. 310-324.
( Abstract | PubMed | PDF )

Professional Activities

Member of the Protein Society, American Society for Cell Biology, Biophysical Society and International Society for Computational Biology.

Co-editor of a special issue on Automated Function Prediction published in BMC Bioinformatics in 2007.

Referee for PLoS Computational Biology, Bioinformatics, Biopolymers, Journal of Structural Biology, BMC Bioinformatics and Proteins.

Scientific Committee Member for "Automated Function Prediction" Conference, San Diego (USA, 2006).

Referee for "Automated Function Prediction" SIG at ISMB, (2005, 2008).

Teaching Experience

Co-supervised a number of undergraduate and postgraduate research projects, University of California, San Diego, USA, (2006)

Co-authored a Collaborative Computational Project for Biomolecular Simulation training workshop on the analysis of biomolecular simulation data. University of Nottingham, UK, (2006).

Developed and co-supervised a number of postgraduate masters student research projects, University of York, UK, (2001-2004)

Teaching Assistant for a number of courses at the University of York including:

  • Structural Bioinformatics, for postgraduate students (2000-2003);
  • Biomolecular Structure, for postgraduate students (2000-2003);
  • Computational Chemistry, for postgraduate students (2000-2003);
  • Chemical Equilibria, for Chemistry undergraduates (2002);
  • Bioinformatics on the World Wide Web, for Biology undergraduates (2002).

Contact Details

Dr. Barry J. Grant
Postdoctoral Associate
University of California, San Diego
Room 4202 Urey Hall
9500 Gilman Dr., La Jolla, CA 92093, USA
bgrant.at.mccammon.ucsd.edu