Gallery of Biomolecular Simulations

Electrostatic channeling: the guided diffusion of an intermediate from one active site to another in a multienzyme complex. Such processes may occur widely in cells, and the modulation of channeling could be a novel element in drug discovery.

Elcock, A.H., J.A. McCammon. Evidence for Electrostatic Channeling in a Fusion Protein of Malate Dehydrogenase and Citrate Synthase. Biochemistry, 35, 12652-12658 (1996).

McCammon Group, UCSD (http://mccammon.ucsd.edu/)
Created by Cameron Mura on Sat Jun 7 17:55:12 PDT 2003.
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